Needle-Free Injection System

Pulse 200, the livestock industry's first needle-free injection system, safely and effectively delivers a 2-ml. dose of medication into an animal, claims Felton International.

Pulse 200 features a pneumatic amplifier designed to place the medication under pressure at the nozzle head. Several pressure settings, appropriate to animal size, can be selected. When pressed firmly against the skin, the pressurized system automatically propels the dose through the skin and into the muscle tissue without breaking the skin.

Brad Thacker, DVM, Iowa State University (ISU), says carcass studies at ISU have shown no gross lesions at the injection site in animals injected with the Pulse 200 system.

The 10-lb. delivery system costs $2,500 and carries a warranty of 250,000 doses.
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Managing Production Variability

Pharmacia Animal Health has introduced a new four-step program to manage variability in pork production operations.

The Consistent Pork Program, launched at the recent International Pig Veterinary Society meeting, helps producers identify targeted interventions using prudent use guidelines to control and manage variation, while capturing otherwise lost financial opportunities.

Step 1 identifies whether variability is an issue, then pinpoints the location and the cost of the problem.

Swine practitioners and producers can use Pharmacia's Total Opportunity Planner to measure the profit lost due to variability. The herd assessment tool enables producers to calculate opportunity costs while setting a benchmark for herd performance. Producers can project income gains by producing pigs of ideal weight.

Step 2 attempts to identify where disease problems occur by using various diagnostic tools, such as Pharmacia's STOMP, a diagnostic program that pinpoints when pigs are becoming infected with respiratory pathogens, so medications can be targeted to do the most good (See “A Strategy to Battle Respiratory Complex,” November 2000). A second, newer tool the company is deploying is called Pathogen Profiling Prioritization, a process where postmortems are done on a few animals to confirm that serology matches pathology.

Step 3 fine-tunes and targets a subpopulation on the farm for intervention, such as lightweight pigs or other pigs at risk.

The final step is to evaluate the effectiveness of the intervention program in improving consistency of production.
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Swine Flu Product

During World Pork Expo, Pfizer Inc. received government approval for its killed swine influenza virus (SIV) bivalent vaccine, proven effective in cross-reacting and cross-protecting against both common subtypes H1N1 and H3N2. FluSure is approved for use alone and in combination as FluSure/RespiSure, FluSure/RespiSure-ONE, FluSure/ER Bac Plus and FluSure/RespiSure-ONE/ER Bac Plus.

All products are approved for use in pigs 3 weeks of age or older. Healthy pigs should receive two, 2-ml. doses about three weeks apart. Semiannual vaccination with a single dose is recommended. Product will be sold in 50- and 250-dose packs. Slaughter withdrawal is 21 days.

FluSure and Pfizer's combination products containing FluSure all feature the adjuvant called Amphigen, which provides enhanced immune response, longer duration of immunity, less injection site irritation and excellent syringeability.

The combination products provide an advantage in timing of vaccination, reducing the need for multiple injections when diagnoses identify presence of the organisms.

In two field studies, Pfizer Animal Health reports that FluSure combination products showed solid protection against both subtypes of SIV. Virus-challenged, vaccinated pigs showed no signs of clinical disease; had reduced shedding, lower body temperatures and much less virus isolated from lungs; and showed significant improvement in lung lesion scores vs. control pigs. Vigorous FluSure combination vaccine tests showed no interference in immune response and conferred excellent protection against H1N1 and H3N2 SIV, mycoplasma and erysipelas antigens.

The FluSure combination vaccines were also confirmed safe based on no injection site reactions in nearly 1,200 pigs vaccinated in field safety and clinical efficacy studies. Sows vaccinated with FluSure were also over 99.5% free of injection site reactions.
(Circle Reply Card No. 103)